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http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 2000 hand curated statements drawn from 57 PubMeds. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All Rights Reserved. http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#_9 http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://purl.org/pav/version 1.6 http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#_8 http://www.w3.org/ns/prov#value We show that protein kinase C (PKC) alpha is translocated to the plasma membrane and activated by adhesion of MM cells to fibronectin and VEGF. We identify beta(1) integrin modulating VEGF-triggered MM cell migration on fibronectin. We show that transient enhancement of MM cell adhesion to fibronectin triggered by VEGF is dependent on the activity of both PKC and beta(1) integrin. Moreover, we demonstrate that PKC alpha is constitutively associated with beta(1) integrin. http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#_8 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11751905 http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#_9 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#_9 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11751905 http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#_8 http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo#pubinfo http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo http://purl.org/dc/terms/created 2014-07-03T14:29:31.168+02:00 http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA-eaWODouBG6qOdasMyNDJCTmFoZW401JNZc5UD0h3Bo http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234