sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_5 ; pav:version "1.4" . sub:_4prov:value "Mutations in hepatocyte nuclear factor 1 alpha (HNF-1A) lead to maturity-onset diabetes of the young type 3 as a result of impaired insulin secretory response in pancreatic Beta-cells. Furthermore the expression of steady-state mRNA levels of gene encoding neutral and neutral and basic amino acid transporter (Nbat) was found to be decreased in Hnf-1-/- mice. In the liver of Hnf-1-/- mice, mRNA levels of Nbat was also reduced by 2.2-fold compared with wild-type littermates, suggesting that HNF-1 alpha leads to the expression of Nbat in pancreatic islets and liver of mice." ; prov:wasQuotedFrompubmed:11679424 . sub:_5rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:11679424 ; prov:wasDerivedFrombeldoc: , sub:_4 . }