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[DDR2 is a tyrosine kinase collagen receptor and is associated with pathological scarring of multiple organs; nevertheless, the functional role of DDR2 in the myocardium remains unclear.George et al. present evidence for the first time that Ang II induces cardiac fibrosis by enhancing DDR2 expression in cardiac fibroblasts via p38 mitogen activated protein kinase (p38 MAPK)-mediated activation of nuclear factor-?B (NF-?B).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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