. . . . . . . "[In recent studies reviewed here, the synergistic effect of TGF? and HER2 on tumor progression has been shown to likely be a combined result of two distinct features: (1) loss of TGF?'s tumor suppressive effect through functional alterations in the anti-mitogenic effect of Smad-mediated transcription, and (2) gain of pro-survival and pro-migratory function through HER2-dependent mechanisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:12:23+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .