http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#Head http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0 http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#assertion http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0 http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#provenance http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0 http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#pubinfo http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#assertion http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_2 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016791 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=3064 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_3 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_4 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_4 http://purl.obolibrary.org/obo/RO_0002204 http://resource.belframework.org/belframework/1.0/namespace/selventa-named-human-protein-families/MAPK%20Erk1%2F3%20Family http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_3 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_1 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#assertion http://www.w3.org/2000/01/rdf-schema#label phos(p(HGNC:DUSP1)) -| kin(p(PFH:"MAPK Erk1/3 Family")) http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_6 http://www.w3.org/ns/prov#value In addition, the constitutively active form of MAPKK (SDSE-MAPKK) suppressed Fas-mediated apoptosis, and MKP-1, a phosphatase specific for classical MAPK, canceled the protective activity of oncogenic K-Ras (K-RasV12), Raf-CAAX, and SDSE-MAPKK. Furthermore, physiological activation of Ras by basic fibroblast growth factor (bFGF) protected Fas-transgenic Balb3T3 cells from Fas-mediated apoptosis. bFGF protection was also dependent on the activation of the MAPK pathway through Ras. All the results indicate that the activation of MAPK through Ras inhibits Fas-mediated apoptosis in Balb3T3 cells, which may play a role in oncogenesis http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10662780 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10662780 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#_6 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0#pubinfo http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0 http://purl.org/dc/terms/created 2014-07-03T14:29:49.933+02:00 http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA2pG5UoCWA9sBaXmi8XcS_6iJL8Hs6V2QiPSi4Iv5Pt0 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234