http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#Head http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#assertion http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#provenance http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#pubinfo http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#assertion http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_2 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0042789 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=9236 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_3 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_4 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0042789 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_4 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6769 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_3 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_1 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#assertion http://www.w3.org/2000/01/rdf-schema#label tscript(p(HGNC:PPARG)) -| tscript(p(HGNC:SMAD3)) http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_6 http://www.w3.org/ns/prov#value suppression of CTGF promoter activity by PPAR gamma activation is completely rescued by overexpression of Smad3, but not by Smad4. Furthermore, PPAR gamma physically interacts with Smad3 but not Smad4 in vitro in glutathione S-transferase pull-down experiments. Taken together, the data suggest that PPAR gamma inhibits TGF-beta-induced CTGF expression in HASMCs by directly interfering with the Smad3 signaling pathway http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11590167 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11590167 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#_6 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U#pubinfo http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U http://purl.org/dc/terms/created 2014-07-03T14:29:58.467+02:00 http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA3XWKhxyPjCHurl_q4U1WpedZgVBkwzPOaylyqsUgM0U http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234