[ {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE",
    "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ],
    "http://www.nanopub.org/nschema#hasAssertion" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#assertion"
    } ],
    "http://www.nanopub.org/nschema#hasProvenance" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#provenance"
    } ],
    "http://www.nanopub.org/nschema#hasPublicationInfo" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#pubinfo"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#Head"
}, {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_1",
    "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0042789" ],
    "http://semanticscience.org/resource/SIO_000139" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_2"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_2",
    "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ],
    "http://purl.obolibrary.org/obo/RO_0002204" : [ {
      "@id" : "http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=7805"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_3",
    "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697" ],
    "http://purl.obolibrary.org/obo/RO_0002204" : [ {
      "@id" : "http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=1662"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_4",
    "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ],
    "http://purl.obolibrary.org/obo/BFO_0000066" : [ {
      "@id" : "http://purl.bioontology.org/ontology/MSH/D022423"
    }, {
      "@id" : "http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_3"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ {
      "@id" : "http://www.selventa.com/vocabulary/directlyIncreases"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_1"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#assertion",
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@value" : "tscript(p(HGNC:NFYB)) => r(HGNC:CD34)"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#assertion"
}, {
  "@graph" : [ {
    "@id" : "http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel",
    "http://purl.org/dc/elements/1.1/description" : [ {
      "@value" : "Approximately 61,000 statements."
    } ],
    "http://purl.org/dc/elements/1.1/rights" : [ {
      "@value" : "Copyright (c) 2011-2012, Selventa. All rights reserved."
    } ],
    "http://purl.org/dc/elements/1.1/title" : [ {
      "@value" : "BEL Framework Large Corpus Document"
    } ],
    "http://purl.org/pav/authoredBy" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_6"
    } ],
    "http://purl.org/pav/version" : [ {
      "@value" : "1.4"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_5",
    "http://www.w3.org/ns/prov#value" : [ {
      "@value" : "Figure 5B shows that addition of either of the two anti-NFYA antibodies to the binding reactions supershifted a prominent complex (lanes 3 and 4) and the anti-NFYB antibody diminished binding significantly (lane 5).   To test the functional effect of NFY binding to the +60/+64 region, we introduced point mutations abolishing the binding of NFY to its site (see Fig 5A and Fig 5B; lane 14) and incorporated them into a luciferase plasmid containing base pairs -391/+175 from the human CD34 promoter (constructs diagramed in Fig 5C). As shown in Fig 5D, mutating the NFY site (Y-M+ construct) resulted in a 5-fold decrease in luciferase activity in transiently transfected KG1a cells and a 4-fold decrease in RPMI-8402 cells, as compared with the wild-type construct (Y+M+ construct)."
    } ],
    "http://www.w3.org/ns/prov#wasQuotedFrom" : [ {
      "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/10572091"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_6",
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@value" : "Selventa"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#assertion",
    "http://www.w3.org/ns/prov#hadPrimarySource" : [ {
      "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/10572091"
    } ],
    "http://www.w3.org/ns/prov#wasDerivedFrom" : [ {
      "@id" : "http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel"
    }, {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#_5"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#provenance"
}, {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE",
    "http://purl.org/dc/terms/created" : [ {
      "@type" : "http://www.w3.org/2001/XMLSchema#dateTime",
      "@value" : "2014-07-03T14:29:49.325+02:00"
    } ],
    "http://purl.org/pav/createdBy" : [ {
      "@id" : "http://orcid.org/0000-0001-6818-334X"
    }, {
      "@id" : "http://orcid.org/0000-0002-1267-0234"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RA3qeLHeqqYAcGR6c3KRYgUnRP3vXrMVF6jEWR5CdX6bE#pubinfo"
} ]