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[Background/Purpose.HMGB1, which may act as a proinflammatory mediator, has been proposed to contribute to the pathogenesis of multiple chronic inflammatory and autoimmune diseases including systemic lupus erythematosus (SLE); however, the precise mechanism of HMGB1 in the pathogenic process of SLE remains obscure.Method.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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