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TextLocation
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Results
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kin(p(HGNC:MAPK7)) -> path(SDIS:"tumor growth")
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Approximately 2000 hand curated statements drawn from 57 PubMeds.
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Copyright (c) 2011-2012, Selventa. All Rights Reserved.
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http://purl.org/dc/elements/1.1/title
BEL Framework Small Corpus Document
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Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License
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1.6
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To investigate whether JNK/AP1 dependency is a general process common to other SCC
cell types, we expressed DNc-Jun in spontaneous human SCC cell lines, A431 and
SCC25, and found that DNc-Jun significantly inhibited their s.c. tumor growth as
well (Fig. 2B–C). Furthermore, retroviral-mediated RNA interference knockdown
of MKK7, the upstream activator of JNK, also prevented s.c. tumor growth of A431,
SCC25, and primary keratinocytes transformed by Ras and IκBα (Fig. 2B–D).
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http://www.ncbi.nlm.nih.gov/pubmed/17440097
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support@belframework.org
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Selventa
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2014-07-03T14:29:32.892+02:00
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