@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RA6Ck6s_6qxhPfYjy5niEeets08NVppAuhwCI8dR1aYa4
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RA6Ck6s_6qxhPfYjy5niEeets08NVppAuhwCI8dR1aYa4#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix mgi: <
http://www.informatics.jax.org/marker/MGI:
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix RNA: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
hasAgent:
sub:_2
;
a
go:0042789
.
sub:_2
geneProductOf:
mgi:98372
;
a
Protein:
.
sub:_3
geneProductOf:
mgi:88061
;
a
RNA:
.
sub:_4
rdf:object
sub:_3
;
rdf:predicate
belv:decreases
;
rdf:subject
go:0006306
;
a
rdf:Statement
.
sub:_5
occursIn:
species:10090
;
rdf:object
sub:_4
;
rdf:predicate
belv:directlyDecreases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"bp(GO:\"DNA methylation\") -| r(MGI:Aprt)" , "tscript(p(MGI:Sp1)) =| (bp(GO:\"DNA methylation\") -| r(MGI:Aprt))" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_7
;
pav:version
"1.4" .
sub:_6
prov:value
"DNA methylation represses transcription in vivo Sp1-like elements have a key role in protecting the CpG island of Aprt (encoding adenine phosphoribosyltransferase) from de novo methylation, and when these elements are specifically mutated, the Aprt CpG island becomes methylated in transgenic mice." ;
prov:wasQuotedFrom
pubmed:10369268
.
sub:_7
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:10369268
;
prov:wasDerivedFrom
beldoc:
,
sub:_6
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:29:47.385+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}