. . . . . . . . . . . . . . . . . "kin(p(HGNC:PRKCA)) -> p(HGNC:PTK2B,pmod(P))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Our results show that VEGF induces the association of CADTK with the b1 integrin/PKCa protein complex...VEGFR immunoprecipitation and immunoblotting studies using anti-Flt-1 and anti-CADTK Abs showed specific constitutive association...VEGF increased (2-fold) fibronectin-induced CADTK tyrosine phosphorylation in MM.1S cells; equivalent loading of proteins was confirmed by stripping and reprobing the membrane with anti-CADTK Ab. The PKC activator PMA enhanced constitutive phosphorylation of CADTK (Fig. 4c). Finally, VEGF-triggered CADTK activation was blocked by both the PKC inhibitor BIM I and a b1 integrin neutralizing mAb...These results indicate that the activation of CADTK in adherent MM cells is influenced by both PKC- and b1 integrin-mediated signaling pathways." . . "Selventa" . . . . "2014-07-03T14:29:59.830+02:00"^^ . . .