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[The lack of the normal isoform of RasGRP1 in some SLE patients and the increased prevalence of defective isoforms of RasGRP1 in others raise the possibility that dysregulation of this signaling protein contributes to the development of autoimmunity in a subset of SLE patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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