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[In PIK3CA-mutant cancer cell lines with persistent mTORC1 signaling despite PI3K p110? blockade (that is, resistance), the addition of the allosteric mTORC1 inhibitor RAD001 to the cells along with BYL719 resulted in reversal of resistance in vitro and in vivo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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