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[We identified 2 novel genes associated with an increased risk of ischemic stroke: a protein-coding variant in PDE4DIP (rs1778155; odds ratio,?2.15; P?=?2.63?�?10(-8)) with an intracellular signal transduction mechanism and in ACOT4 (rs35724886; odds ratio,?2.04; P?=?1.24?�?10(-7)) with a fatty acid metabolism; confirmation of PDE4DIP was observed in affected sibpair families with large-vessel stroke subtype and in African Americans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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Gene-disease associations inferred from text-mining the literature.
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