@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAFnrjX2KrKo9AOYzlxmGAZjxXw3rqjIbtO4EcXXw1UwQ> .
@prefix sub: <http://purl.org/np/RAFnrjX2KrKo9AOYzlxmGAZjxXw3rqjIbtO4EcXXw1UwQ#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/HP_0002017> biolink:category biolink:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/HP_0002017>;
    rdf:predicate biolink:treats;
    rdf:subject <https://identifiers.org/CHEBI:52993>;
    a rdf:Statement;
    rdfs:label "Off-label (non-FDA-approved) uses for Lorazepam include rapid tranquilization of the agitated patient, alcohol withdrawal delirium, alcohol withdrawal syndrome, insomnia, panic disorder, delirium, chemotherapy-associated anticipatory nausea and vomiting (adjunct or breakthrough), as well as psychogenic catatonia.";
    biolink:association_type biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    biolink:has_population_context sub:cohort;
    biolink:provided_by <https://w3id.org/um/NeuroDKG>;
    biolink:publications <https://pubmed.ncbi.nlm.nih.gov/30422485>;
    biolink:relation nkg:OffLabelIndication .
  
  sub:cohort rdfs:label "adults";
    biolink:category biolink:Cohort;
    biolink:has_phenotype <https://identifiers.org/MONDO:0005070> .
  
  <https://identifiers.org/CHEBI:52993> biolink:category biolink:Drug .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "Wxs3soyQ0EcBGgz2EyygiZC0gzHiTLVPeMfCdikswE8/rP1Q7DoZBKOTl9ggU3ZL0CG7zULPkK2NrwHuNSbeJd+y2rI0BWquuibBeuzpurKWBYrE+gMeaha2mCZA8Lb7RGaaMadYs/GHXlTsiNHuilUP/5o/aQKz4Y8hj1jmfa4=";
    npx:hasSignatureTarget this: .
  
  this: dcterms:created "2021-05-01T10:09:23.616+02:00"^^xsd:dateTime;
    dcterms:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAZdZj78B6nKrP1Q00oFzsK07u7WdiY3sToz-H-H2nSgg> .
}