@prefix dc: <http://purl.org/dc/terms/> .
@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAGBmZJNa2Qc2dRQ17RDoaHDBG8ELEmbTVIkUQ2wUSP3U> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAGBmZJNa2Qc2dRQ17RDoaHDBG8ELEmbTVIkUQ2wUSP3U#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix proteinModification: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000> .
@prefix psimod: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAnnotation: <http://semanticscience.org/resource/SIO_000255> .
@prefix atcc: <http://www.lgcstandards-atcc.org/Products/All/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 belv:variantOf hgnc:3236;
    a proteinModification:, psimod:01148 .
  
  sub:_2 belv:degradationOf sub:_3 .
  
  sub:_3 geneProductOf: hgnc:3236;
    a Protein: .
  
  sub:_4 occursIn: atcc:CRL-11268.aspx, species:9606;
    hasAnnotation: sub:_5;
    rdf:object sub:_2;
    rdf:predicate belv:directlyIncreases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:_5 dc:subject "TextLocation";
    rdf:value "Abstract" .
  
  sub:assertion rdfs:label "p(HGNC:EGFR,pmod(U,K)) => deg(p(HGNC:EGFR))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved.";
    dce:title "BEL Framework Small Corpus Document";
    dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License";
    pav:authoredBy sub:_7;
    pav:version "1.6" .
  
  sub:_6 prov:value """Here we tested whether the related human LRIG1 (also called Lig-1) protein can act
as a negative regulator of EGF receptor and its relatives, ErbB2, ErbB3, and ErbB4.
We observed that in co-transfected 293T cells, LRIG1 forms a complex with
each of the ErbB receptors independent of growth factor binding. We further observed
that co-expression of LRIG1 with EGF receptor suppresses cellular receptor
levels, shortens receptor half-life, and enhances ligand-stimulated receptor ubiquitination.""";
    prov:wasQuotedFrom pubmed:15345710 .
  
  sub:_7 rdfs:comment "support@belframework.org";
    rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:15345710;
    prov:wasDerivedFrom beldoc:, sub:_6 .
}

sub:pubinfo {
  this: dc:created "2014-07-03T14:29:34.115+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}