. . . . . . . "[Upon stimulation of mouse macrophages, the levels of I?B?, which inhibits NF-?B, fell but low pH prevented its later increase, which normally restores the baseline activity of NF-?B, even though the levels of mRNA for I?B? were increased. pH 7.0 greatly increased and prolonged NF-?B binding to its consensus promoter sequence, especially the anti-inflammatory p50:p50 homodimers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:14:59+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .