. . . . . . . "[Although the pathogenic nature of this mutation needs further confirmation, our findings suggest that the A? N-terminal region potentially modulates APP processing and A? aggregation, and further provides a genetic indication of the importance of Zn(2+) and Cu(2+) in the etiology of AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:10:38+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .