. . . . . . . "[Interestingly, we observed marked deficiency of LRP1 and upregulation of TGF-? in cells from affected individuals, the latter being consistent with available data on the role of TGF-? in the remodeling of the sclera in myopia and the high frequency of myopia in individuals with Marfan syndrome who characteristically have upregulation of TGF-? signaling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:14:21+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .