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[Here, we find that activation of Hh signaling is positively correlated with NF-?B pathway in DLBCL tumors, and that smoothened (SMO), the signal transducer subunit of Hh pathway, contributes to NF-?B activation through recruiting G protein subunits G?i and G?12 to activate PKC?/CARMA1/TRAF6/NEMO signaling axis followed by assembling of the CARMA1/BCL10/MALT1/TRAF6 complex to SMO.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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