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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA#_6 http://www.w3.org/ns/prov#value Significant expression of Vcam-1 was observed in wild-type mice on day 6 following intranasal challange with OVA, while very faint or no Vcam-1 expression was seen in identically OVA sensitized/ challenged IL12 Knockout mice. Scores of Vcam-1 staining showed a significant less Vcam-1 expression in IL12 KO mice. The supplement of recombinant IL12 (rIL12) to IL12 KO mice significantly increased the expression of Vcam-1. The Vcam-1 expression score in rIL12-treated mice was 1.17, while the score in IL-12 KO mice without rIL-12 treatment was 0.17 (p < 0.05). These results indicate that IL-12 increased the expression of Vcam-1. http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11160340 http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11160340 http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA#_6 http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA#pubinfo http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA http://purl.org/dc/terms/created 2014-07-03T14:29:54.012+02:00 http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAQV9Gy3-nJlaYnfVx3657nP50L8MON8uA-_AbEObBJxA http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234