@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAR1w226G1jmVGX5nFlvHIYMO8HFZwE5tvm8RSoKArV2I
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAR1w226G1jmVGX5nFlvHIYMO8HFZwE5tvm8RSoKArV2I#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix pfm: <
http://resource.belframework.org/belframework/1.0/namespace/selventa-named-mouse-protein-families/
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix RNA: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697
> .
@prefix mgi: <
http://www.informatics.jax.org/marker/MGI:
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix mesh: <
http://purl.bioontology.org/ontology/MSH/
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
hasAgent:
sub:_2
;
a
go:0042789
.
sub:_2
geneProductOf:
pfm:Notch%20Family
;
a
Protein:
.
sub:_3
geneProductOf:
mgi:104556
;
a
RNA:
.
sub:_4
occursIn:
mesh:D012867
,
mesh:D015603
,
species:10090
;
rdf:object
sub:_3
;
rdf:predicate
belv:increases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"tscript(p(PFM:\"Notch Family\")) -> r(MGI:Cdkn1a)" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_6
;
pav:version
"1.4" .
sub:_5
prov:value
"When Notch-IC is present, however, it competes with the inhibitory proteins to bind to CSL. Notch1-IC also directly stimulates expression of the cell-cycle regulator Waf1 (also known as Cip1 and p21) in primary mouse keratinocytes25. The increase in Waf1 concentration causes proliferating keratinocytes to withdraw from the cell cycle and helps to initiate terminal differentiation." ;
prov:wasQuotedFrom
pubmed:14570040
.
sub:_6
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:14570040
;
prov:wasDerivedFrom
beldoc:
,
sub:_5
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:30:17.578+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}