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kin(p(HGNC:PRKCB)) => p(HGNC:PARP1,pmod(P))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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1.4
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<N15> DNA-PK is ADP ribosylated by PARP in vitro, and the protein kinase activity (including p53 and RPA substrates) is thereby stimulated (Ruscetti et al., 1998). (PARP is phosphorylated by DNA-PK [Ruscetti et al., 1998], but the consequences of this are unknown; therefore, this reaction is not included in the chart.) <N16> PARP is phosphorylated at a serine and a threonine site by PKCa and b in vitro, as a consequence of which PARP binding to DNA is weakened, and PARP activity is reduced (Bauer et al., 1992).
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Selventa
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2014-07-03T14:29:47.908+02:00
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