sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_7 ; pav:version "1.4" . sub:_6prov:value "IL-6-induced Association of Gab1 and Gab2 with SHP2 Is Hck-mediated.....IL-6-induced tyrosine phosphorylation of Gab1 and Gab2, as well as their association with SHP2, were markedly decreased in MM cells with kinase-inactive Hck versus MM cells with wild-type Hck. In anti-Grb2 immunoprecipitates, IL-6-induced tyrosine phosphorylation of Gab1 and Gab2, but not their association with Grb2, was abrogated (Fig. 6b). Taken together, these data further confirm that IL-6-induced Gab protein tyrosine phosphorylation and formation of Gab/Grb2·SHP2-containing protein complexes is dependent on Hck activity." ; prov:wasQuotedFrompubmed:15010462 . sub:_7rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:15010462 ; prov:wasDerivedFrombeldoc: , sub:_6 . }