. . . . . . . . . . . . . . . . . . . . . "a(CHEBI:nicotine) -| complex(p(HGNC:E2F1),p(HGNC:RB1))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "in vitro kinase assays showed that the kinase activity associated with cyclins D and E was greatly enhanced upon nicotine stimulation (Figure 1, E and F). Furthermore, nicotine stimulation led to the dissociation of E2F1 from Rb as assessed by IP/Western blot analysis (Figure 1G, top panel), correlating with the induction of cyclin D/cdk4 and cyclin E/cdk2 activity as well as Rb phosphorylation (Figure 1G, middle 2 panels)." . . "Selventa" . . . . "2014-07-03T14:30:45.331+02:00"^^ . . .