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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RASIBtK5l3YKcF-_wVfwcde9Cv106ShWTqAdF2RePzqDU#_6 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RASIBtK5l3YKcF-_wVfwcde9Cv106ShWTqAdF2RePzqDU#_5 http://www.w3.org/ns/prov#value Notch signaling, which promotes keratinocyte differentiation, is upregulated in embryonic keratinocyte and epidermis, and elevated caspase 3 expression, which we identify as a transcriptional Notch1 target, accounts in part for the high commitment of embryonic keratinocytes to terminal differentiation. Table 1. Genes Concomitantly Upregulated in Embryonic Keratinocytes and in Response to Increased Notch1 Activity Figure 3. 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