. . . . . . . "[Together, these results indicate that the SDF-1?/CXCL12-CXCR4 signaling pathway interfaces with the classical endocrine pathway to up-regulate GH production via suppression of inhibin ?-C. Because it blocks CXCR4 and prevents hypoxia-induced down-regulation of inhibin ?-C expression, AMD3100 has promise as a molecular-targeting agent in the treatment of GH-producing adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:16:08+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .