sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_6 ;
pav:version "1.4" .
sub:_4 dce:identifier "Entrez Gene SUmmary E2F2" ;
dce:title "Entrez Gene SUmmary E2F2" ;
dce:type "Online Resource" .
sub:_5 prov:value "Entrez Gene summary: Human: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1." ;
prov:wasQuotedFrom sub:_4 .
sub:_6 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource sub:_4 ;
prov:wasDerivedFrom beldoc: ,
sub:_5 .
}