http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#head
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://www.nanopub.org/nschema#hasAssertion
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#assertion
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://www.nanopub.org/nschema#hasProvenance
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#provenance
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://www.nanopub.org/nschema#hasPublicationInfo
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#publicationInfo
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.nanopub.org/nschema#Nanopublication
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#assertion
http://rdf.disgenet.org/resource/gda/DGN899ad5ccefc297617eae7b05de38d446
http://semanticscience.org/resource/SIO_000628
http://identifiers.org/ncbigene/595
http://rdf.disgenet.org/resource/gda/DGN899ad5ccefc297617eae7b05de38d446
http://semanticscience.org/resource/SIO_000628
http://linkedlifedata.com/resource/umls/id/C0006142
http://rdf.disgenet.org/resource/gda/DGN899ad5ccefc297617eae7b05de38d446
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://semanticscience.org/resource/SIO_001123
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#provenance
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#assertion
http://purl.org/dc/terms/description
[Five lines of evidence suggest that melatonin works via epigenetic processes: (1) melatonin influences transcriptional activity of nuclear receptors (ERalpha, GR and RAR) involved in the regulation of breast cancer cell growth; (2) melatonin down-regulates the expression of genes responsible for the local synthesis or activation of estrogens including aromatase, an effect which may be mediated by methylation of the CYP19 gene or deacetylation of CYP19 histones; (3) melatonin inhibits telomerase activity and expression induced by either natural estrogens or xenoestrogens; (4) melatonin modulates the cell cycle through the inhibition of cyclin D1 expression; (5) melatonin influences circadian rhythm disturbances dependent on alterations of the light/dark cycle (i.e., light at night) with the subsequent deregulation of PER2 which acts as a tumor suppressor gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#assertion
http://purl.org/ontology/wi/core#evidence
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#assertion
http://semanticscience.org/resource/SIO_000772
http://identifiers.org/pubmed/18592373
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#assertion
http://www.w3.org/ns/prov#wasDerivedFrom
http://rdf.disgenet.org/v5.0.0/void/BEFREE
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#assertion
http://www.w3.org/ns/prov#wasGeneratedBy
http://purl.obolibrary.org/obo/ECO_0000203
http://rdf.disgenet.org/v5.0.0/void/BEFREE
http://purl.org/pav/importedOn
2017-02-19
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://purl.obolibrary.org/obo/ECO_0000212
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://www.w3.org/2000/01/rdf-schema#comment
Gene-disease associations inferred from text-mining the literature.
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://www.w3.org/2000/01/rdf-schema#label
DisGeNET evidence - LITERATURE
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU#publicationInfo
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/dc/terms/created
2017-10-17T13:10:50+02:00
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/dc/terms/rights
http://opendatacommons.org/licenses/odbl/1.0/
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/dc/terms/rightsHolder
http://rdf.disgenet.org/v5.0.0/void/IBIGroup
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/dc/terms/subject
http://semanticscience.org/resource/SIO_000983
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/net/provenance/ns#usedData
http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/pav/authoredBy
http://orcid.org/0000-0001-5999-6269
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/pav/authoredBy
http://orcid.org/0000-0002-7534-7661
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/pav/authoredBy
http://orcid.org/0000-0002-9383-528X
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/pav/authoredBy
http://orcid.org/0000-0003-0169-8159
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/pav/authoredBy
http://orcid.org/0000-0003-1244-7654
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/pav/createdBy
http://orcid.org/0000-0003-0169-8159
http://rdf.disgenet.org/resource/nanopub/NP102316.RAU91_XyzyHq7GpbAt7g7NPgttXIHu70HfoA-wC51_TWU
http://purl.org/pav/version
v5.0.0.0
http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf
http://purl.org/pav/version
v5.0.0