. . . . . . . . . . . . . . . . "kin(p(HGNC:MAPK3)) -| cat(complex(NCH:\"proton-transporting ATP synthase complex\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Activation of PKC-a mediated the sustained decrease in mitochondrial membrane hyperpolarisation and oxidative phosphorylation but not the decrease in electron transfer rate. Sustained mitochondrial dysfunction was also affected by ERK1/2, through a PKC-independent pathway. These findings suggest that activation of PKC-a and/or ERK1/2 lead to decreased activity of ATP synthase, rather than affecting OXPHOS system complexes [40]. Indeed, the a, b, and e subunits of F(1)F(0)- ATPase have PKC consensus motifs [41]. PKC-a phosphorylated the b subunit of F(1)F(0)-ATPase on a serine residue and decreased F(0)F(1)-ATPase activity, oxidative phosphorylation and ATP production [41]." . . "Selventa" . . . . "2014-07-03T14:30:42.452+02:00"^^ . . .