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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I#_6 http://www.w3.org/ns/prov#value Both apha2M and a2M* bind a variety of cytokines and growth factors, including FGF1, FGF2, FGF4, and FGF6, but not FGF5, FGF7, FGF9, and FGF10 [161]. The binding of a2M to FGF2 occurs with high affinity (Table 1) and is primarily hydrophobic in nature [162]. a2M sequesters FGF2 in the extracellular environment and inhibits its cell interaction, protease-inducing activity [163] and mitogenic capacity [161]. http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15863032 http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15863032 http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I#_6 http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I#pubinfo http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I http://purl.org/dc/terms/created 2014-07-03T14:30:34.759+02:00 http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAUR5KcWWFZiIPm9b1vE_22jrnAqg7L_1Ju2L_Zgzhu7I http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234