@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAUfOBNG8GmDwDjQN6mv6kkd1f5IvYI6Tb_nmxshxdbxM> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAUfOBNG8GmDwDjQN6mv6kkd1f5IvYI6Tb_nmxshxdbxM#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix schem: <http://resource.belframework.org/belframework/1.0/namespace/selventa-legacy-chemical-names/> .
@prefix RNA: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697> .
@prefix mgi: <http://www.informatics.jax.org/marker/MGI:> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: mgi:104663;
    a RNA: .
  
  sub:_2 occursIn: species:10090;
    rdf:object sub:_1;
    rdf:predicate belv:increases;
    rdf:subject schem:serum%20insulin;
    a rdf:Statement .
  
  sub:assertion rdfs:label "a(SCHEM:\"serum insulin\") -> r(MGI:Lep)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_5;
    pav:version "1.4" .
  
  sub:_3 dce:identifier "Biochemistry of Lipids, Lipoproteins and Membranes 2002 - Chapter 10";
    dce:title "Biochemistry of Lipids, Lipoproteins and Membranes 2002 - Chapter 10";
    dce:type "Book" .
  
  sub:_4 prov:value "Leptin receptors are members of the class 1 cytokine receptor family and are linked to JAK-STAT signalling systems. The short term regulatin of leptin expression is influenced by a number of factors that regulate CEBP alpha and PPAR gama activity on the leptin promotor.  ...Insulin, glucose, and glucocorticoids induce ob (leptin) espression. while fasting, cold exposure, beta3 agonists, catecholamine stimulation and thiazolidinediones all decrease leptin expression.  Leptin works to suppress appetite by affecting the synthesis and or action of a complex system of neuropeptides including neuropeptide Y, MCH, POMC, alphaMSH, all of which directly or indirectly influence food intake.";
    prov:wasQuotedFrom sub:_3 .
  
  sub:_5 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource sub:_3;
    prov:wasDerivedFrom beldoc:, sub:_4 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:29:45.540+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}