[ { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI", "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ], "http://www.nanopub.org/nschema#hasAssertion" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#assertion" } ], "http://www.nanopub.org/nschema#hasProvenance" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#provenance" } ], "http://www.nanopub.org/nschema#hasPublicationInfo" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#pubinfo" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#Head" }, { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#_1", "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0042789" ], "http://semanticscience.org/resource/SIO_000139" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#_2" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#_2", "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ], "http://purl.obolibrary.org/obo/RO_0002204" : [ { "@id" : "http://www.informatics.jax.org/marker/MGI:109247" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#_3", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ], "http://purl.obolibrary.org/obo/BFO_0000066" : [ { "@id" : "http://purl.bioontology.org/ontology/MSH/D008264" }, { "@id" : "http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#_1" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "http://www.selventa.com/vocabulary/increases" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=7583" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#assertion", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "a(CHEBI:\"nitric oxide\") -> tscript(p(MGI:Ddit3))" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#assertion" }, { "@graph" : [ { "@id" : "http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel", "http://purl.org/dc/elements/1.1/description" : [ { "@value" : "Approximately 61,000 statements." } ], "http://purl.org/dc/elements/1.1/rights" : [ { "@value" : "Copyright (c) 2011-2012, Selventa. All rights reserved." } ], "http://purl.org/dc/elements/1.1/title" : [ { "@value" : "BEL Framework Large Corpus Document" } ], "http://purl.org/pav/authoredBy" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#_5" } ], "http://purl.org/pav/version" : [ { "@value" : "1.4" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#_4", "http://www.w3.org/ns/prov#value" : [ { "@value" : "We reported that the endoplasmic reticulum (ER) stress pathway involving CHOP, a member of the C/EBP transcription factor family, plays a key role in nitric oxide (NO)-mediated apoptosis of macrophages and pancreatic beta cells. We also showed that the cytosolic chaperone pair of hsp70 and dj1 (hsp40/hdj-1) or dj2 (HSDJ/hdj-2) prevents NO-mediated apoptosis upstream of cytochrome c release from mitochondria. To analyze roles of the chaperone pair in preventing apoptosis, RAW 264.7 macrophages stably expressing hsp70 and dj1 or dj2 were established. The chaperone pair prevented LPS/IFN-gamma-induced and NO-mediated apoptosis downstream of CHOP induction." } ], "http://www.w3.org/ns/prov#wasQuotedFrom" : [ { "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/14752510" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#_5", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "Selventa" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#assertion", "http://www.w3.org/ns/prov#hadPrimarySource" : [ { "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/14752510" } ], "http://www.w3.org/ns/prov#wasDerivedFrom" : [ { "@id" : "http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel" }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#_4" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#provenance" }, { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI", "http://purl.org/dc/terms/created" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#dateTime", "@value" : "2014-07-03T14:30:20.033+02:00" } ], "http://purl.org/pav/createdBy" : [ { "@id" : "http://orcid.org/0000-0001-6818-334X" }, { "@id" : "http://orcid.org/0000-0002-1267-0234" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RAUhAtCDOiUODR6tM8mUWtJNlCJegEWaZjo-DjiStcNbI#pubinfo" } ]