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TextLocation
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Results
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bp(GOBP:"cellular response to electrical stimulus") -> kin(p(SFAM:"CAMK2 Family"))
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Approximately 2000 hand curated statements drawn from 57 PubMeds.
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Copyright (c) 2011-2012, Selventa. All Rights Reserved.
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BEL Framework Small Corpus Document
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Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License
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1 h of 10-Hz train stimulation significantly increased (P < 0.01) the mean nuclear
stain of activated CaMKII compared with unstimulated fibers, and KN-62 (5 μM)
blocked the increase in activated CaMKII staining after stimulation (Fig. 3 A).
In parallel experiments, in which the fibers were stained with antibody directed
against total CaMKII, there was no difference in mean nuclear antibody stain between
stimulated and unstimulated fibers (P > 0.05; Fig. 3 A). These results are
consistent with activation of nuclear CaMKII by fiber electrical stimulation without
any appreciable translocation of CaMKII from the cytoplasm to the nucleus.
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support@belframework.org
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Selventa
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2014-07-03T14:31:16.375+02:00
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