@prefix dc: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix prov: .
@prefix Protein: .
@prefix hgnc: .
@prefix geneProductOf: .
@prefix hasPart: .
@prefix ProteinComplex: .
@prefix hasAnnotation: .
@prefix atcc: .
@prefix occursIn: .
@prefix species: .
@prefix pubmed: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
sub:_1 hasPart: sub:_2, sub:_3;
occursIn: atcc:CRL-11268.aspx, species:9606;
hasAnnotation: sub:_4;
a ProteinComplex: .
sub:_2 geneProductOf: hgnc:3432;
a Protein: .
sub:_3 geneProductOf: hgnc:17360;
a Protein: .
sub:_4 dc:subject "TextLocation";
rdf:value "Abstract" .
sub:assertion rdfs:label "complex(p(HGNC:ERBB4),p(HGNC:LRIG1))" .
}
sub:provenance {
beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds.";
dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved.";
dce:title "BEL Framework Small Corpus Document";
dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License";
pav:authoredBy sub:_6;
pav:version "1.6" .
sub:_5 prov:value """Here we tested whether the related human LRIG1 (also called Lig-1) protein can act
as a negative regulator of EGF receptor and its relatives, ErbB2, ErbB3, and ErbB4.
We observed that in co-transfected 293T cells, LRIG1 forms a complex with
each of the ErbB receptors independent of growth factor binding. We further observed
that co-expression of LRIG1 with EGF receptor suppresses cellular receptor
levels, shortens receptor half-life, and enhances ligand-stimulated receptor ubiquitination.""";
prov:wasQuotedFrom pubmed:15345710 .
sub:_6 rdfs:comment "support@belframework.org";
rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:15345710;
prov:wasDerivedFrom beldoc:, sub:_5 .
}
sub:pubinfo {
this: dc:created "2014-07-03T14:29:34.110+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}