. . . . . . . . . . . . . . . . . "tscript(p(PFH:\"NOTCH Family\")) -> r(HGNC:ERBB2)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "the oncogenic effects of Notch include phosphatidylinositol 3-kinase (PI3K) activation and induction of ERBB2 and NF-?B2 expression. The mechanism by which PI3K is activated by NOTCH1-IC is not known, but the induction of ERBB2 and NF-?B2 - the promoters of which contain CSL-binding sites - is almost certainly mediated by the transactivation function of NOTCH1-IC. PI3K signalling confers resistance to anoikis 80,81 and p53-mediated apoptosis 82, whereas ERBB2 stimulates proliferation and growth of cells." . . "Selventa" . . . . "2014-07-03T14:30:17.586+02:00"^^ . . .