http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#Head http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#assertion http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#provenance http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#pubinfo http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#assertion http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_2 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0042789 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_2 http://purl.obolibrary.org/obo/RO_0002204 http://resource.belframework.org/belframework/1.0/namespace/selventa-named-human-protein-families/NOTCH%20Family http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_3 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=3430 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.bioontology.org/ontology/MSH/D012867 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.bioontology.org/ontology/MSH/D015603 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_3 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_1 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#assertion http://www.w3.org/2000/01/rdf-schema#label tscript(p(PFH:"NOTCH Family")) -> r(HGNC:ERBB2) http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_6 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_5 http://www.w3.org/ns/prov#value the oncogenic effects of Notch include phosphatidylinositol 3-kinase (PI3K) activation and induction of ERBB2 and NF-?B2 expression. The mechanism by which PI3K is activated by NOTCH1-IC is not known, but the induction of ERBB2 and NF-?B2 - the promoters of which contain CSL-binding sites - is almost certainly mediated by the transactivation function of NOTCH1-IC. PI3K signalling confers resistance to anoikis 80,81 and p53-mediated apoptosis 82, whereas ERBB2 stimulates proliferation and growth of cells. http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/14570040 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/14570040 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#_5 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk#pubinfo http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk http://purl.org/dc/terms/created 2014-07-03T14:30:17.586+02:00 http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAVeMSUMoO32wtk8tp400nJHTbw37USmwh-YYNxJbsqmk http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234