@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAVgiIK7J013fHGFF4wPo9_FH5yx0zRI2gCDXs5J4VFCk> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAVgiIK7J013fHGFF4wPo9_FH5yx0zRI2gCDXs5J4VFCk#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasPart: <http://purl.obolibrary.org/obo/BFO_0000051> .
@prefix ProteinComplex: <http://amigo.geneontology.org/amigo/term/GO:0043234> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 geneProductOf: hgnc:10848 ;
    a Protein: .
  sub:_2 hasPart: sub:_3 , sub:_4 ;
    a ProteinComplex: .
  sub:_3 geneProductOf: hgnc:9585 ;
    a Protein: .
  sub:_4 geneProductOf: hgnc:11119 ;
    a Protein: .
  sub:_5 occursIn: mesh:D012867 , species:9606 ;
    rdf:object sub:_2 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "p(HGNC:SHH) -> complex(p(HGNC:PTCH1),p(HGNC:SMO))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_7 ;
    pav:version "1.4" .
  sub:_6 prov:value "The diagram depicts the Sonic hedgehog (SHH)-GLI pathway and shows the transduction of the SHH signal through the Smoothend (SMO)/Patched (PTC) receptor complex. In the absence of the SHH ligand,PTC represses SMO. Signalling is initiated by the binding of SHH to PTC,which relieves the repression of SMO. Subsequently, SMO signals to the nucleus by increasing the concentration of GLI transcription factors,which recruit co-activators to activate downstream target genes." ;
    prov:wasQuotedFrom pubmed:14570040 .
  sub:_7 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:14570040 ;
    prov:wasDerivedFrom beldoc: , sub:_6 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:30:17.566+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}