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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q#_3 http://www.w3.org/ns/prov#value H(2)O(2)-induced nuclear export of TERT is preceded by TERT tyrosine phosphorylation at position 707 and prevented by the Src kinase family inhibitor PP1. Oxidative stress-induced nuclear export of TERT depends on association with the Ran GTPase. In contrast, mutation of tyrosine 707 inhibits phosphorylation induced by oxidative stress and prevents association with Ran and nuclear export of TERT. Moreover, inhibition of tyrosine phosphorylation at 707 increases the antiapoptotic capacity of TERT. http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12808100 http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12808100 http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q#_3 http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q#pubinfo http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q http://purl.org/dc/terms/created 2014-07-03T14:30:13.583+02:00 http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAWANikX4fobGQ4qFjDoi2d_bZ4DJJK1pGWpoTlQd3D_Q http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234