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[Thus, some early genetic events such as the loss of RANKL and the gain of CXCR4 expressions probably facilitate the metastatic progression concomitant with the primary tumor establishment, supporting the role of the CXCR4 receptor in directing osteosarcoma metastases to the lung.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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