sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "1.4" .
  sub:_4 prov:value "FROM TEXT and Figure 6: Hybridization to the U133A DNA microarray,Genes downregulated in NANOG overexpressing cells and 2- day-old EBs compared with wild-type ES cells (Fig. 6D). These may be ICM (and therefore ES cell) markers that are downregulated upon the transition to primitive ectoderm. Among these genes are LECTIN (LGALS1), a known marker of HESCs (Dvash et al., 2004) that is absent from all samples but ES cells, and HOXA1 (homeo box A1), a transcription factor involved in development. Among the genes downregulated in NANOG overexpressing cells but to a smaller extent are genes suggested to be downstream targets of HOXA1 (Shen et al., 2000), such as GBX2 and BMP2." ;
    prov:wasQuotedFrom pubmed:16501172 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:16501172 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}