@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAXoIG6tAwK5-ejmP8_lrarwBLvbxtLqXDYEKGKOXnU7c> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAXoIG6tAwK5-ejmP8_lrarwBLvbxtLqXDYEKGKOXnU7c#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix proteinModification: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix atcc: <http://www.lgcstandards-atcc.org/Products/All/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 belv:hasSubstitution "R,273,H" ;
    belv:variantOf hgnc:11998 ;
    a proteinModification: .
  sub:_2 occursIn: atcc:HTB-38.aspx , species:9606 ;
    rdf:object go:0008283 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "p(HGNC:TP53,sub(R,273,H)) -> bp(GO:\"cell proliferation\")" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_4 ;
    pav:version "1.4" .
  sub:_3 prov:value "These activities range from enhanced proliferation in culture, to increased tumorigenicity in vivo, and enhanced resistance to a variety of anticancer drugs commonly used in clinical practice cloned into the pRetroSuper vector were transfected into SKBR3 cells, carrying the p53R175H mutant, and into HT29 and SW480, carrying the p53R273H or the p53R273H/P309S mutants," ;
    prov:wasQuotedFrom pubmed:16170357 .
  sub:_4 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:16170357 ;
    prov:wasDerivedFrom beldoc: , sub:_3 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:30:38.261+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}