http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#Head http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#assertion http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#provenance http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#pubinfo http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#assertion http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_2 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6877 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_3 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_4 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_4 http://purl.obolibrary.org/obo/RO_0002204 http://resource.belframework.org/belframework/1.0/namespace/selventa-named-human-protein-families/ROCK%20Family http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_3 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_1 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#assertion http://www.w3.org/2000/01/rdf-schema#label kin(p(HGNC:MAPK3)) -| kin(p(PFH:"ROCK Family")) http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_6 http://www.w3.org/ns/prov#value We show that the sustained ERK-MAP kinase signalling resulting from transformation by oncogenic Ras down-regulates ROCK1 and Rho-kinase, two Rho effectors required for actin stress fibre formation. The repression of Rho- dependent stress fibre formation by ERK-MAP kinase signalling http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11179220 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11179220 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#_6 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI#pubinfo http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI http://purl.org/dc/terms/created 2014-07-03T14:29:54.260+02:00 http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAXtE1fzDDQGROMDWKUtjnb1mZgeADalDef7-7rMgCatI http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234