http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#Head http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#assertion http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#provenance http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#pubinfo http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#assertion http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_2 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=1773 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_3 http://www.selventa.com/vocabulary/variantOf http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=9884 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00696 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.bioontology.org/ontology/MSH/D003593 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_4 http://semanticscience.org/resource/SIO_000255 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_5 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_3 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/directlyIncreases http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_1 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_5 http://purl.org/dc/terms/subject TextLocation http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#value Review http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#assertion http://www.w3.org/2000/01/rdf-schema#label kin(p(HGNC:CDK4)) => p(HGNC:RB1,pmod(P)) http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#provenance http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 2000 hand curated statements drawn from 57 PubMeds. http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All Rights Reserved. http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Small Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/dc/terms/license Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_7 http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_6 http://www.w3.org/ns/prov#value They also repress transcription of cyclin D1 and D2, which results in an attenuation of CDK4 activity and reduced phosphorylation of Rb protein, and hence increased binding activity of E2F family members to Rb. http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15917664 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_7 http://www.w3.org/2000/01/rdf-schema#comment support@belframework.org http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15917664 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#_6 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU#pubinfo http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU http://purl.org/dc/terms/created 2014-07-03T14:31:17.973+02:00 http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAYOJQu4YN3Bka3HTGl7xhrx3HMpa5JLBxBTmo9aKmAvU http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234