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http://purl.obolibrary.org/obo/RO_0002204
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http://resource.belframework.org/belframework/1.0/namespace/selventa-legacy-chemical-names/Lysophosphatidylserine
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a(SCHEM:Lysophosphatidylserine) -> (p(RGD:Ngf) -> p(RGD:Il6))
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http://www.w3.org/2000/01/rdf-schema#label
p(RGD:Ngf) -> p(RGD:Il6)
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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1.4
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We have observed that NGF at doses as low as 10 ng/ml will induce IL-6 production and inhibit TNF-alpha release from rat peritoneal mast cells in the presence of lysophosphatidylserine as a cofactor. NGF synergizes with LPS treatment of peritoneal mast cells (PMC) for the induction of IL-6. Examination of the mechanism of this phenomenon has revealed that NGF can induce both rat PMC and mouse bone marrow-derived cultured mast cells to produce substantial levels of PGE2.
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Selventa
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2014-07-03T14:29:46.772+02:00
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