sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_6 ;
pav:version "1.4" .
sub:_5 prov:value "Vasoactive intestinal peptide binding to VPAC(2) on CD4 T cells specifically induces an up-regulation of the Th2-type transcription factors c-Maf and JunB, which consequently enhances IL-4 and IL-5 production, leading to a Th2-type phenotype. There is strong evidence to support requirements for c-Maf, JunB, and NFAT in promoting IL-4 production. JunB, a member of the AP-1 transcription factor family, acts synergistically with c-maf to strongly activate IL-4 expression, and has also been shown to be required for IL-5 expression in Th2 cells (17, 29)." ;
prov:wasQuotedFrom pubmed:15187104 .
sub:_6 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:15187104 ;
prov:wasDerivedFrom beldoc: ,
sub:_5 .
}