@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAYmhF6HhW4cIPlqaoPgFSnc8UVar5aOmyGFuQWnPzY4A
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAYmhF6HhW4cIPlqaoPgFSnc8UVar5aOmyGFuQWnPzY4A#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix proteinModification: <
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000
> .
@prefix psimod: <
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
hasAgent:
sub:_2
;
a
go:0016301
.
sub:_2
geneProductOf:
hgnc:795
;
a
Protein:
.
sub:_3
belv:variantOf
hgnc:1100
;
a
proteinModification:
,
psimod:00696
.
sub:_4
occursIn:
species:9606
;
rdf:object
sub:_3
;
rdf:predicate
belv:directlyIncreases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"kin(p(HGNC:ATM)) => p(HGNC:BRCA1,pmod(P,S))" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_6
;
pav:version
"1.4" .
sub:_5
prov:value
"First, BRCA1 is a target for phosphorylation by several of the protein serine/threonine kinases (for example, ATM, ATR and CHK2) that signal the presence of DNA breakage46, and its modification by these enzymes seems essential for further participation in mechanisms that enforce cell-cycle checkpoints that are triggered by DNA damage in the S and G2 phases of the cell cycle47-49." ;
prov:wasQuotedFrom
pubmed:15057286
.
sub:_6
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:15057286
;
prov:wasDerivedFrom
beldoc:
,
sub:_5
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:30:22.191+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}