sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "1.4" .
  sub:_4 prov:value "Throughout evolution, pathogen-induced stimulation of the innate immune system relies on numerous conserved Toll-like receptors (TLRs), which initiate intracellular signaling cascades that subsequently activate the transcription factors NF-B and AP-1 [43 and 44]. NF-B controls a wide variety of immune-inducible antimicrobial molecules, including ROS and RNS, as well as cytokines and co-stimulatory molecules [45]. Binding sites for NF-B and AP-1, as well as for response elements for cytokines, have been identified in the 5' UTR (untranslated region) of the human XOR gene and both NF-B and XOR are stimulated by bacterial lipopolysaccharids (LPS) in vivo [28, 46 and 47]. This suggests that XOR is a downstream target of the TLR-NF-B pathway and is directly activated by NF-B and AP-1." ;
    prov:wasQuotedFrom pubmed:12967676 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:12967676 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}