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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAZ18EC4VMh9RyIC-zhvIUbrnBkG6ewcCVK2mO1CZESV8#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAZ18EC4VMh9RyIC-zhvIUbrnBkG6ewcCVK2mO1CZESV8#_6 http://www.w3.org/ns/prov#value Truncation of signal transducer and activator of transcription (STAT) 5 at the carboxy-terminal domain, either by genetic engineering or by proteolytic cleavage, results in generation of dominant-negative forms. Nuclear element is not necessary for calpain-mediated STAT5 cleavage, since this process occurs in platelets. 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