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p(HGNC:ITGB1) -> p(HGNC:CDC42)
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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1.4
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Cell attachment to fibronectin activated Cdc42 within 20 minutes in ECV 304 cells by an integrin-dependent manner. Attachment through ITGB1 to fibronectin activated Cdc42 thereby increasing the proteolysis of CDKN1A. Transient overexpression of N17Cdc42 blocked the reduction of CDKN1A caused by adhesion to fibronectin, indicating that integrin-induced signaling through Cdc42 increases the proteolysis of CDKN1A.
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Selventa
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2014-07-03T14:30:03.613+02:00
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